By Nasuhi Engin AydinEpigenetic defects of stromal cells in endometriosis and adenomyosis lead to estrogen sensitivity
By Nasuhi Engin Aydin
Serdar Bulun, MD, J.J. Sciarra Professor and Chair Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois has delivered a conference on “Endometriosis and adenomyosis: single-cell genome-wide approaches” at the Annual International Medical Conference of the Endometriosis Foundation…
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By Dr. Youngran ParkInhibition of Histone methyltransferase for fighting endometriosis
By Dr. Youngran Park
Although the histone methyltransferase EZH2 and its product H3K27me3 are well studied in cancer, little is known about their role and potential as therapeutic targets in endometriosis. It has been previously reported that the endometriotic lesions are characterized by global…
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Epigenetic regulation of the pathological process in endometriosis.
By Dr. Youngran Park
Epigenetic mechanisms have been recognized as important players in the development of a broad range of human diseases including endometriosis. A growing body of evidence shows that the remodeling of retrograde endometrial tissues to the ectopic endometriotic lesions involves multiple epigenetic…
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